Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 5/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724023 | 1.00 | KCNA3 (0.49) | KCNA3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL4231721 | 0.90 | DRD2 (0.55) | HTR2AKDM4DDRD2DRD4DRD3 | |
| SCHEMBL2030049 | 0.90 | DRD2 (0.55) | HTR2AKDM4DDRD2DRD4DRD3 | |
| SCHEMBL7724067 | 0.88 | KCNA3 (0.59) | KCNA3CTSKDRD2DRD4 | |
| SCHEMBL7724060 | 0.88 | KCNA3 (0.59) | KCNA3CTSKDRD2DRD4 | |
| SCHEMBL23579702 | 0.88 | KCNA3 (0.53) | KCNA3HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL3351581 | 0.85 | SIGMAR1 (0.60) | KCNA3HTR2ADRD3CCR3 | |
| SCHEMBL8257331 | 0.84 | KCNA3 (0.56) | KCNA3HRH1DRD2DRD4DRD3 | |
| SCHEMBL30902315 | 0.83 | UTS2R (0.48) | KCNA3HTR7KDM4DNPY5RCTSK | |
| SCHEMBL30401098 | 0.83 | KCNA3 (0.55) | KCNA3DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |