SCHEMBL7724157

SCHEMBL7724157

N#COc1c(Cl)cc(-c2cc(Cl)c(OC#N)c(Cl)c2)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.36
AHR P35869 3/20 0.31
CYP1B1 Q16678 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2590122 0.81 HSP90AA1 (0.35)
SCHEMBL5935272 0.79 CYP3A4 (0.34)
SCHEMBL7722961 0.76 CA1 (0.38) AHR
SCHEMBL830568 0.76 AR (0.33)
SCHEMBL15569634 0.75
SCHEMBL11854817 0.75 KMT2A (0.38)
SCHEMBL11778727 0.75 CYP3A4 (0.42)
SCHEMBL2035807 0.73 HTR2A (0.31)
SCHEMBL10659248 0.72 POLB (0.33)
SCHEMBL1742688 0.70 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337375-B1 RESIN WITH COLOR AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-01-08 US disclosed
US-6190759-B1 ELECTRONIC PACKAGE COMPRISING DIELECTRIC LAYER AND CONDUCTIVE LAYER, SAID DIELECTRIC LAYER INCLUDING REINFORCING MATERIAL, RESIN MATERIAL SELECTED FROM EPOXY, CYANATE AND BISMALEIMIDE RESINS, COLORING AGENT, AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-20 US disclosed
US-6187417-B1 Substrate having high optical contrast and method of making same INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-13 US disclosed
US-5605781-A Photosensitive composition with cyanate esters and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-02-25 US disclosed
US-5464726-A Making resist image by exposing positive photosensitive composition /cyanate ester and cationic photoinitiator generating Bronsted acid upon exposure to actinic light/ in predetermined pattern to actinic light, heating, developing INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1995-11-07 US disclosed
EP-0147547-B1 PREPARATION OF AROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1989-11-15 EP disclosed
EP-0147548-B1 NOVEL POLYAROMATIC CYANATES AND POLYTRIAZINES PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1989-09-13 EP disclosed
EP-0180649-B1 NOVEL CATALYSTS FOR THE PRODUCTION OF POLYTRIAZINES FROM AROMATIC POLYCYANATES THE DOW CHEMICAL COMPANY (US) 1988-11-30 EP disclosed
US-4751323-A MONOMERS FOR POLYTRIAZINE, POLYCANURATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US disclosed
US-4748270-A Preparation of aromatic cyanates THE DOW CHEMICAL COMPANY (US) 1988-05-31 US disclosed
US-4713442-A FOR HYDROLYSIS-RESISTANT POLYCYANURATES THE DOW CHEMICAL COMPANY (US) 1987-12-15 US disclosed
EP-0180649-A1 Novel catalysts for the production of polytriazines from aromatic polycyanates THE DOW CHEMICAL COMPANY (US) 1986-05-14 EP disclosed
EP-0147547-A2 Preparation of aromatic cyanates THE DOW CHEMICAL COMPANY (US) 1985-07-10 EP disclosed
US-4528366-A Production of polytriazines from aromatic polycyanates with cobalt salt of a carboxylic acid as catalyst THE DOW CHEMICAL COMPANY (US) 1985-07-09 US disclosed
WO-1985002184-A1 POLYAROMATIC CYANATES, A PROCESS FOR PREPARING THE POLYAROMATIC CYANATES, AND POLYTRIAZINES PREPARED FROM THE POLYAROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1985-05-23 WO disclosed
WO-1985002185-A1 A PROCESS FOR THE PREPARATION OF AROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1985-05-23 WO disclosed
US-4195132-A CROSSLINKING BY WAT OF TRIAZINE RINGS BAYER AKTIENGESELLSCHAFT (DE) 1980-03-25 US disclosed
US-4116946-A OLEFIN, CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-4094852-A Process for the production of polytriazines in the presence of high-boiling esters BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4031067-A Polytriazines and a process for their production BAYER AKTIENGESELLSCHAFT (DT) 1977-06-21 US disclosed