SCHEMBL7724200

SCHEMBL7724200

C=Cc1ccc(CC(Cc2ccccc2)(C(=O)O)C(=O)OC(C)(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTPN1 P18031 5/20 0.41
PTPN2 P17706 1/20 0.40
PTPRA P18433 1/20 0.40
PTPRB P23467 1/20 0.40
PPARA Q07869 5/20 0.36
PPARG P37231 4/20 0.36
MMP8 P22894 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
LMNA P02545 1/20 0.36
PTPRC P08575 1/20 0.36
THRA P10827 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5144144 0.82 THRA (0.38) ALDH1A1CYP3A4CYP2C9CYP2C19PPARA
SCHEMBL14668505 0.82 THRA (0.38) ALDH1A1CYP3A4CYP2C9CYP2C19PPARA
SCHEMBL28134677 0.81 PTPN1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL5144194 0.80 MMP8 (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL9167412 0.80 PTPN1 (0.39) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL15268442 0.79 SMN1; SMN2 (0.45) ALDH1A1CYP3A4PTPN1PTPN2PTPRA
SCHEMBL5142209 0.79 ELANE (0.38) ALDH1A1CYP3A4CYP2C9CYP2C19PPARA
SCHEMBL5142208 0.78 MMP8 (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL5144303 0.77 THRA (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19PTPN1
SCHEMBL13101217 0.76 THRA (0.37) ALDH1A1CYP3A4CYP2C9CYP2C19PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399273-B1 Water-processable photoresist compositions BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM 2002-06-04 US disclosed