Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | NQO2 | P16083 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108561 | 0.91 | KDM4E (0.44) | PRMT1NQO2ALDH1A1TOP1HPGD | |
| SCHEMBL6531598 | 0.83 | PRMT1 (0.50) | PRMT1NQO2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8349629 | 0.83 | TAAR1 (0.47) | PRMT1ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL549139 | 0.82 | SETD7 (0.58) | ALDH1A1HPGDHSD17B10MITFLMNA | |
| SCHEMBL7724245 | 0.81 | NQO2 (0.50) | PRMT1NQO2ALDH1A1TOP1HPGD | |
| Hydrochloric Acid SCHEMBL5963346 | 0.81 | SETD7 (0.56) | ALDH1A1HPGDHSD17B10MITFLMNA | |
| SCHEMBL7732998 | 0.80 | HTT (0.41) | PRMT1NQO2ALDH1A1TOP1HPGD | |
| SCHEMBL7735075 | 0.79 | NQO2 (0.47) | PRMT1NQO2ALDH1A1TOP1HPGD | |
| SCHEMBL549147 | 0.77 | NQO2 (0.50) | PRMT1NQO2ALDH1A1TOP1HPGD | |
| SCHEMBL8346288 | 0.75 | TAAR1 (0.45) | ALDH1A1HPGDCASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792271-B1 | FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM | UNIV GEORGIA STATE RES FOUND (US) | 2002-02-27 | — | — | EP | claimed |
| CN-1681511-A | Combinations of drugs for the treatment of neoplasms | COMBINATORX INC (US) | 2005-10-12 | — | — | CN | disclosed |
| EP-0792271-B1 | FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM | UNIV GEORGIA STATE RES FOUND (US) | 2002-02-27 | — | — | EP | disclosed |