Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 11/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 3/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL549147 | 0.82 | NQO2 (0.50) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL26108561 | 0.82 | KDM4E (0.44) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL27612097 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HPGDTDP1 | |
| SCHEMBL7724232 | 0.81 | PRMT1 (0.45) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL7735075 | 0.81 | NQO2 (0.47) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL7732998 | 0.79 | HTT (0.41) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| Hydrochloric Acid SCHEMBL26105399 | 0.79 | ALDH1A1 (0.52) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL26102912 | 0.76 | NPC1 (0.48) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL5482696 | 0.76 | NQO2 (0.59) | NQO2PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL26108922 | 0.76 | NQO2 (0.53) | NQO2PRMT1ALDH1A1TOP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792271-B1 | FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM | UNIV GEORGIA STATE RES FOUND (US) | 2002-02-27 | — | — | EP | claimed |
| EP-0792271-B1 | FURAN DERIVATIVES FOR INHIBITING PNEUMOCYSTIS CARINII PNEUMONIA, GIARDIA LAMBLIA AND CRYPTOSPORIDIUM PARVUM | UNIV GEORGIA STATE RES FOUND (US) | 2002-02-27 | — | — | EP | disclosed |