Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | MC4R | P32245 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724258 | 1.00 | SIGMAR1 (0.60) | SIGMAR1MC4RSMN1; SMN2DRD4CXCR3 | |
| SCHEMBL7725101 | 0.89 | SIGMAR1 (0.61) | SIGMAR1MC4RSMN1; SMN2DRD4CXCR3 | |
| SCHEMBL7725104 | 0.89 | SIGMAR1 (0.61) | SIGMAR1MC4RSMN1; SMN2DRD4CXCR3 | |
| SCHEMBL7729551 | 0.88 | HTR2A (0.51) | SIGMAR1DRD4HTR2ADRD2 | |
| SCHEMBL7719806 | 0.88 | HTR2A (0.51) | SIGMAR1DRD4HTR2ADRD2 | |
| SCHEMBL7724046 | 0.82 | SIGMAR1 (0.54) | SIGMAR1MC4RSMN1; SMN2DRD4CXCR3 | |
| SCHEMBL7724053 | 0.82 | SIGMAR1 (0.54) | SIGMAR1MC4RSMN1; SMN2DRD4CXCR3 | |
| SCHEMBL7724049 | 0.82 | SIGMAR1 (0.54) | SIGMAR1MC4RSMN1; SMN2DRD4CXCR3 | |
| SCHEMBL7724256 | 0.81 | SIGMAR1 (0.57) | SIGMAR1MC4RDRD4CXCR3HTR2A | |
| SCHEMBL7724311 | 0.80 | SIGMAR1 (0.56) | SIGMAR1MC4RDRD4CXCR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337034-B1 | COMPOUNDS HAVING WIDE TEMPERATURE RANGE OF LIQUID CRYSTAL PHASE, LOW VISCOSITY, LOW THRESHOLD VOLTAGE AND EXCELLENT STABILITY, WHICH ARE READILY MIXED WITH VARIOUS LIQUID CRYSTAL MATERIALS AND GOOD IN SOLUBILITY AT LOW TEMPERATURE | CHISSO CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0885875-A1 | VINYLENE COMPOUNDS AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1998-12-23 | — | — | EP | disclosed |