Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433099 | 0.90 | THRA (0.48) | THRATHRB | |
| SCHEMBL1101443 | 0.88 | THRA (0.54) | THRATHRB | |
| SCHEMBL777282 | 0.87 | DHODH (0.48) | DHODHCA12CA1CA2CA5A | |
| SCHEMBL30408777 | 0.87 | THRA (0.56) | THRATHRBLTB4RLTB4R2 | |
| SCHEMBL5028619 | 0.87 | THRA (0.56) | THRATHRBLTB4RLTB4R2 | |
| Ammonia Solution, Strong SCHEMBL371312 | 0.87 | THRA (0.52) | THRATHRB | |
| SCHEMBL6028371 | 0.87 | THRA (0.56) | THRATHRBLTB4RLTB4R2 | |
| SCHEMBL327172 | 0.87 | THRA (0.56) | THRATHRBLTB4RLTB4R2 | |
| SCHEMBL2918461 | 0.87 | THRA (0.56) | THRATHRBLTB4RLTB4R2 | |
| SCHEMBL29240382 | 0.87 | THRA (0.56) | THRATHRBLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395825-B1 | REACTING TETRACHLOROSILANE OR A TRICHLOROSILANE IN MIXTURE COMPRISING HYDROCHLORIC ACID, NON-POLAR SOLVENT AND ORGANIC SULFATE; COATINGS, PROTECTIVE BARRIERS, ELECTRONICS | DOW CORNING CORPORATION | 2002-05-28 | — | — | US | disclosed |