SCHEMBL7724408

SCHEMBL7724408

CCCc1ccc(OS(=O)(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.50
ENPP1 P22413 1/20 0.49
CA2 P00918 1/20 0.48
ALDH1A1 P00352 1/20 0.45
PLA2G1B P04054 1/20 0.43
KMT2A Q03164 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
STS P08842 4/20 0.43
LPL P06858 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
PLK1 P53350 1/20 0.42
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
ALPL P05186 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14015390 0.89 CA2 (0.51) THRBCA2ALDH1A1STSPLK1
SCHEMBL3950036 0.87 THRB (0.54) THRBCA2ALDH1A1KMT2ASTS
SCHEMBL3374605 0.86 THRB (0.54) THRBCA2ALDH1A1KMT2ASTS
SCHEMBL29240379 0.86 THRB (0.54) THRBCA2ALDH1A1KMT2ASTS
SCHEMBL4062463 0.86 THRB (0.54) THRBCA2ALDH1A1KMT2ASTS
SCHEMBL11654904 0.86 THRB (0.54) THRBCA2ALDH1A1KMT2ASTS
SCHEMBL15672842 0.84 THRB (0.52) THRBCA2ALDH1A1KMT2ASTS
SCHEMBL27635693 0.84 THRB (0.52) THRBCA2ALDH1A1KMT2ASTS
SCHEMBL236312 0.84 SMN1; SMN2 (0.47) CA2ALDH1A1KMT2ASTSLMNA
Ammonia Solution, Strong SCHEMBL9821317 0.82 SMN1; SMN2 (0.50) CA2ALDH1A1KMT2ASTSPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395825-B1 REACTING TETRACHLOROSILANE OR A TRICHLOROSILANE IN MIXTURE COMPRISING HYDROCHLORIC ACID, NON-POLAR SOLVENT AND ORGANIC SULFATE; COATINGS, PROTECTIVE BARRIERS, ELECTRONICS DOW CORNING CORPORATION 2002-05-28 US disclosed