SCHEMBL7724503

SCHEMBL7724503

Cc1ccc(-c2cccc(C)c2S(=O)(=O)O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CA1 P00915 1/20 0.42
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
PTGS2 P35354 4/20 0.38
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MCOLN3 Q8TDD5 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
DAO P14920 1/20 0.37
PTGS1 P23219 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7053927 0.87 CA12 (0.43) CA12CA2CA9CA1KMT2A
SCHEMBL5167481 0.84 MEN1 (0.42) CA12CA2CA9CA1KMT2A
SCHEMBL27891278 0.83 CA12 (0.38) CA12CA2CA9CA1SMN1; SMN2
SCHEMBL7624639 0.83 HDAC4 (0.46) KMT2AMEN1PTGS2LMNASMN1; SMN2
SCHEMBL183903 0.78 ALDH1A1 (0.43) CA2CA9CA1POLBSMN1; SMN2
SCHEMBL10905332 0.78 SMN1; SMN2 (0.50) CA12CA2CA9CA1KMT2A
SCHEMBL4378653 0.77 NAT1 (0.35) ALDH1A1HTTGAA
SCHEMBL11076120 0.76 ALDH1A1 (0.42) CA2CA9CA1POLBSMN1; SMN2
Water SCHEMBL8773033 0.76 ALDH1A1 (0.42) CA2CA9CA1POLBSMN1; SMN2
Hydrochloric Acid SCHEMBL8629651 0.76 ALDH1A1 (0.42) CA2CA9CA1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6403801-B1 MIXING IN LIQUID MEDIUM STRONG BASE, ARYL HALIDE OR ARYL PSEUDOHALIDE, ARYLBORONIC ACID, NICKEL, PALLADIUM OR PLATINUM COMPOUND, N-HETEROCYCLIC CARBENE SELECTED FROM IMIDAZOLINE-2-YLIDENE, BIS(IMIDAZOLINE-2-YLIDENE) OR SALTS UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION 2002-06-11 US claimed
WO-2001066248-A2 C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) 2001-09-13 WO claimed