SCHEMBL7724604

SCHEMBL7724604

Cc1cc(Cl)cc(O)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
TSHR P16473 5/20 0.56
HSD17B10 Q99714 5/20 0.56
HPGD P15428 3/20 0.56
CYP3A4 P08684 5/20 0.52
ALOX15 P16050 2/20 0.52
CHRM1 P11229 1/20 0.52
MAOA P21397 1/20 0.52
TBXA2R P21731 1/20 0.52
ADRA1A P35348 1/20 0.52
HTR2B P41595 1/20 0.52
MAPT P10636 2/20 0.45
GAA P10253 1/20 0.45
HSP90AA1 P07900 1/20 0.40
RAPGEF4 Q8WZA2 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
RECQL P46063 1/20 0.38
SIRT1 Q96EB6 1/20 0.36
ESR2 Q92731 1/20 0.36
ACLY P53396 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2172009 0.81 ALDH1A1 (0.46) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL6053398 0.80 HSD17B10 (0.72) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL765882 0.80 CYP3A4 (0.58) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL69908 0.79 CYP3A4 (0.75) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL3719666 0.79 CYP3A4 (0.52) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL7723814 0.79 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL30433819 0.79 CYP3A4 (0.52) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL2933421 0.79 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL28732224 0.76 CYP3A4 (0.55) ALDH1A1TSHRHSD17B10HPGDCYP3A4
SCHEMBL23409555 0.75 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10HPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337375-B1 RESIN WITH COLOR AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-01-08 US disclosed
EP-1145083-A2 HYBRID SURFACE MODIFICATION PROCESS AND ARTICLE BMC Industries, Inc. (US) 2001-10-17 EP disclosed
US-6190759-B1 ELECTRONIC PACKAGE COMPRISING DIELECTRIC LAYER AND CONDUCTIVE LAYER, SAID DIELECTRIC LAYER INCLUDING REINFORCING MATERIAL, RESIN MATERIAL SELECTED FROM EPOXY, CYANATE AND BISMALEIMIDE RESINS, COLORING AGENT, AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-20 US disclosed
US-6187417-B1 Substrate having high optical contrast and method of making same INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-13 US disclosed
WO-2000073856-A2 PATTERN FORMING PROCESS COMPRISING CHEMICAL MACHINING AND ELECTRICAL DISCHARGE MACHINING BMC INDUSTRIES, INC. (US) 2000-12-07 WO disclosed
EP-0534204-B1 Base developable negative photoresist and use thereof IBM (US) 1997-06-04 EP disclosed
US-5629355-A Polymeric sulfonium salt photoinitiators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-05-13 US disclosed
US-5605781-A Photosensitive composition with cyanate esters and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-02-25 US disclosed
EP-0375929-B1 Method for patterning cationic curable photoresist IBM (US) 1997-01-29 EP disclosed
US-5550171-A Polymeric sulfonium salt photoinitiators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-08-27 US disclosed
US-4483961-A Polymeric cyclopentadiene derivatives, method for preparing and use thereof ASHLAND OIL, INC. (US) 1984-11-20 US disclosed
US-4482653-A Cyclopentadiene derivatives, method for preparing, and use thereof ASHLAND OIL, INC. (US) 1984-11-13 US disclosed
US-4464521-A EPOXIDIZED FULVENES AS BINDER FOR AGGREGATE; FOUNDRY BINDERS ASHLAND OIL, INC. (US) 1984-08-07 US disclosed
US-4412088-A CURABLE BINDER COMPOSITIONS ASHLAND OIL, INC. (US) 1983-10-25 US disclosed
US-4410647-A POLYANHYDRIDE, 2-ACETOXYTRIMETHYLENEBIS/ANHYDROTRIMELLITATE/ INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1983-10-18 US disclosed
US-4390675-A EPOXYFULVENE, ACID CATALYST ASHLAND OIL, INC. (US) 1983-06-28 US disclosed
EP-0053280-A1 Sealing composition, method for preparing said composition, integrated circuit module sealed therewith, and process for sealing International Business Machines Corporation (US) 1982-06-09 EP disclosed
EP-0009190-B1 CURABLE COMPOSITION USEFUL FOR SCREEN-PRINTING, A CURED COATING COMPRISING SAID COMPOSITION AND PROCESS FOR SOLDERING PRINTED CIRCUIT BOARDS USING SAID COMPOSITION International Business Machines Corporation (US) 1982-04-28 EP disclosed
US-4292230-A Screen-printing composition and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1981-09-29 US disclosed
EP-0009190-A1 Curable composition useful for screen-printing, a cured coating comprising said composition and process for soldering printed circuit boards using said composition International Business Machines Corporation (US) 1980-04-02 EP disclosed