Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135862 | 0.90 | STAT3 (0.52) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL11272932 | 0.85 | STAT3 (0.49) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL7737277 | 0.85 | STAT3 (0.49) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL7794014 | 0.85 | STAT3 (0.51) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL9644793 | 0.83 | ALDH1A1 (0.50) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL5870519 | 0.81 | STAT3 (0.51) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL34472509 | 0.80 | STAT3 (0.50) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL23150848 | 0.79 | STAT3 (0.47) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL10458162 | 0.78 | STAT3 (0.54) | STAT3CTDSP1SIRT5CA1CA2 | |
| SCHEMBL7342597 | 0.78 | STAT3 (0.57) | STAT3CTDSP1SIRT5CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410528-B1 | FUNGICIDES, ANTIPROTOZOA AGENT | GLAXO WELLCOME S.A. (ES) | 2002-06-25 | — | — | US | disclosed |