SCHEMBL7794014

SCHEMBL7794014

C=C(F)COS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 2/20 0.51
CTDSP1 Q9GZU7 1/20 0.45
SIRT5 Q9NXA8 1/20 0.45
GAA P10253 2/20 0.42
ALDH1A1 P00352 5/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP13 P45452 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CYP2D6 P10635 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CA12 O43570 1/20 0.39
CA3 P07451 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3135862 0.87 STAT3 (0.52) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL5870519 0.86 STAT3 (0.51) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL7724652 0.85 STAT3 (0.48) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL34472509 0.84 STAT3 (0.50) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL23150848 0.83 STAT3 (0.47) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL7737277 0.83 STAT3 (0.49) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL11272932 0.83 STAT3 (0.49) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL7342597 0.81 STAT3 (0.57) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL10458162 0.81 STAT3 (0.54) STAT3CTDSP1SIRT5GAAALDH1A1
SCHEMBL9644793 0.80 ALDH1A1 (0.50) STAT3CTDSP1SIRT5GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9221441-A None JP disclosed
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
CN-114173787-A Dihydropyrimidine derivatives and their use in the treatment of HBV infection or HBV-induced diseases 杨森科学爱尔兰无限公司 2022-03-11 CN disclosed
EP-0821050-B1 Optically active compound and antiferroelectric liquid crystal composition containing the same SEMICONDUCTOR ENERGY LAB (JP) 2001-11-28 EP disclosed
US-5820782-A LOW THRESHOLD VOLTAGE AND LOW VISCOSITY; PYRIMIDINE-BASED COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-10-13 US disclosed
EP-0821050-A1 Optically active compound and antiferroelectric liquid crystal composition containing the same Takasago International Corporation (JP) 1998-01-28 EP disclosed
JP-H09221441-A OPTICALLY ACTIVE COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME, LIQUID CRYSTAL ELEMENT HAVING THE COMPOSITION AND DISPLAY USING THE ELEMENT CANON INC 1997-08-26 JP disclosed