Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723380 | 1.00 | RXRA (0.50) | RXRARXRBRXRGMCL1PTGER1 | |
| SCHEMBL7730068 | 0.89 | RXRA (0.47) | RXRARXRBRXRGMCL1PTGER1 | |
| SCHEMBL7723395 | 0.85 | RXRA (0.44) | RXRARXRBRXRGMCL1PTGER1 | |
| SCHEMBL7723397 | 0.85 | RXRA (0.44) | RXRARXRBRXRGMCL1PTGER1 | |
| SCHEMBL7093065 | 0.77 | HTR2B (0.42) | ALDH1A1HPGD | |
| SCHEMBL7724475 | 0.77 | HTR2B (0.42) | ALDH1A1HPGD | |
| SCHEMBL4556877 | 0.76 | RXRA (0.51) | RXRARXRBRXRGMCL1PTGER1 | |
| SCHEMBL7724616 | 0.75 | RXRA (0.50) | RXRARXRBRXRGMCL1PTGER1 | |
| SCHEMBL15942243 | 0.74 | RXRA (0.49) | RXRARXRBRXRGMCL1PTGER1 | |
| SCHEMBL15942310 | 0.74 | RXRA (0.49) | RXRARXRBRXRGMCL1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403623-B1 | ADMINISTERING 2-(2-SUBSTITUTED-PHENYL)-2-OXAZOLINES AND RELATED 5-MEMBERED HETEROCYCLES | UNUVERSITY OF NOTRE DAME DU LAC | 2002-06-11 | — | — | US | disclosed |
| US-6310058-B1 | N-HYDROXYAZEPIN-2-ONES SUBSTITUTED AT 3 POSITION WITH A GROUP CONTAINING A 2-PHENYLOXAZOLE OR 2-PHENYLOXAZOLINE GROUP FOR TREATING TUBERCULOSIS | UNIVERSITY OF NOTRE DAME DU LAC | 2001-10-30 | — | — | US | disclosed |