SCHEMBL7724915

SCHEMBL7724915

CCOC(=O)CCCOc1ccc(CCCC(=O)OC)cc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.48
ALOX5 P09917 1/20 0.46
FAAH O00519 1/20 0.45
LTA4H P09960 4/20 0.44
MAPT P10636 1/20 0.44
DHFR P00374 2/20 0.43
C5AR1 P21730 1/20 0.43
HPGD P15428 1/20 0.43
CYP4Z1 Q86W10 1/20 0.42
CYP4F11 Q9HBI6 1/20 0.42
CYP4F12 Q9HCS2 1/20 0.42
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7737515 0.90 THRA (0.49) PTPN1ALOX5LTA4HMAPTC5AR1
SCHEMBL7737650 0.89 THRA (0.53) PTPN1C5AR1THRATHRB
SCHEMBL7735769 0.87 PTPN1 (0.49) PTPN1MAPTC5AR1HPGDTHRA
SCHEMBL7734829 0.87 PTPN1 (0.48) PTPN1MAPTC5AR1HPGDTHRA
SCHEMBL7735854 0.87 PTPN1 (0.48) PTPN1MAPTC5AR1HPGDTHRA
SCHEMBL7734111 0.85 PTPN1 (0.49) PTPN1MAPTC5AR1HPGDTHRA
SCHEMBL7735802 0.84 PTPN1 (0.54) PTPN1MAPTHPGDCYP4F2CYP4A11
SCHEMBL27429004 0.84 PPARG (0.46) PTPN1ALOX5FAAHLTA4HDHFR
SCHEMBL7725111 0.84 PTPN1 (0.56) PTPN1ALOX5C5AR1THRATHRB
SCHEMBL7725102 0.84 PTPN1 (0.48) PTPN1MAPTC5AR1HPGDTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376546-B1 ANTIALLERGENS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-04-23 US disclosed
EP-1024130-A1 BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-08-02 EP disclosed