Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737650 | 0.97 | THRA (0.53) | THRATHRBPTPN1KDM4EPPARG | |
| SCHEMBL7725111 | 0.94 | PTPN1 (0.56) | THRATHRBPTPN1KDM4EPPARG | |
| SCHEMBL7734899 | 0.91 | PTPN1 (0.55) | THRATHRBPTPN1KDM4EPPARG | |
| SCHEMBL7724915 | 0.90 | PTPN1 (0.48) | THRATHRBPTPN1C5AR1MAPT | |
| SCHEMBL7734829 | 0.90 | PTPN1 (0.48) | THRATHRBPTPN1KDM4EC5AR1 | |
| SCHEMBL7735854 | 0.90 | PTPN1 (0.48) | THRATHRBPTPN1KDM4EC5AR1 | |
| SCHEMBL7724925 | 0.89 | THRA (0.52) | THRATHRBKDM4EPPARGPPARA | |
| SCHEMBL7737444 | 0.88 | THRA (0.51) | THRATHRBKDM4EPPARGPPARA | |
| SCHEMBL7734111 | 0.88 | PTPN1 (0.49) | THRATHRBPTPN1KDM4EPPARG | |
| SCHEMBL7735769 | 0.88 | PTPN1 (0.49) | THRATHRBPTPN1KDM4EC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376546-B1 | ANTIALLERGENS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |