Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725077 | 1.00 | HTR2A (0.46) | HTR2AHTR2CHTR7HTR6CCR3 | |
| SCHEMBL7725075 | 1.00 | HTR2A (0.46) | HTR2AHTR2CHTR7HTR6CCR3 | |
| SCHEMBL7724046 | 0.89 | SIGMAR1 (0.54) | HTR2ADRD2DRD4SIGMAR1 | |
| SCHEMBL7724049 | 0.89 | SIGMAR1 (0.54) | HTR2ADRD2DRD4SIGMAR1 | |
| SCHEMBL7724053 | 0.89 | SIGMAR1 (0.54) | HTR2ADRD2DRD4SIGMAR1 | |
| SCHEMBL7729553 | 0.89 | HTR2A (0.52) | HTR2AHTR2CHTR7HTR6CCR3 | |
| SCHEMBL7729559 | 0.89 | HTR2A (0.52) | HTR2AHTR2CHTR7HTR6CCR3 | |
| SCHEMBL7719856 | 0.85 | HTR2A (0.43) | HTR2AHTR2CHTR7HTR6CCR3 | |
| SCHEMBL7719855 | 0.85 | HTR2A (0.43) | HTR2AHTR2CHTR7HTR6CCR3 | |
| SCHEMBL7719806 | 0.83 | HTR2A (0.51) | HTR2AHTR2CHTR7HTR6CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |