Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13350324 | 0.86 | PDE4A (0.46) | PDE4APDE4DPDE4BPDE4CSSTR5 | |
| SCHEMBL7724823 | 0.83 | PDE4A (0.42) | PDE4APDE4DPDE4BPDE4CSSTR5 | |
| SCHEMBL7725505 | 0.81 | PDE4A (0.49) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL7724896 | 0.79 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL6974761 | 0.79 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4CSSTR5 | |
| SCHEMBL8325337 | 0.78 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4CSSTR5 | |
| Hydrochloric Acid SCHEMBL7724907 | 0.78 | PDE4A (0.46) | PDE4APDE4DPDE4BPDE4CSSTR5 | |
| SCHEMBL7733975 | 0.78 | PDE4D (0.49) | PDE4APDE4DPDE4BPDE4CALDH1A1 | |
| SCHEMBL8354087 | 0.77 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4CSSTR5 | |
| SCHEMBL8324871 | 0.75 | PDE4A (0.46) | PDE4APDE4DPDE4BPDE4CSSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |