Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772443 | 0.91 | PRKCA (0.43) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL774776 | 0.90 | PRKCA (0.46) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL773991 | 0.87 | PRKCA (0.46) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL774480 | 0.87 | PRKCA (0.50) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL774060 | 0.86 | PRKCA (0.48) | PRKCAMMP12NR1I2SCN9ARPS6KA3 | |
| SCHEMBL774469 | 0.86 | PRKCA (0.44) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL774468 | 0.85 | PRKCA (0.49) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL772485 | 0.85 | PRKCA (0.45) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL12429031 | 0.85 | PRKCA (0.43) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL771922 | 0.84 | PRKCA (0.43) | PRKCAMMP12CYP3A4CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | POLI, TERT, ZC3HAV1 | PRKCA 2404/4885MMP12 1013/4885CYP3A4 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.