Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592728 | 0.93 | MAPT (0.51) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL5712400 | 0.90 | LMNA (0.48) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL11652184 | 0.90 | LMNA (0.53) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL10417803 | 0.88 | LMNA (0.52) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL9849076 | 0.86 | LMNA (0.60) | MAPTMAPK1LMNAPRKCAPRKCE | |
| Ethylene Glycol SCHEMBL4914065 | 0.86 | FFAR4 (0.46) | MAPTMAPK1LMNAALDH1A1MEN1 | |
| SCHEMBL2706936 | 0.86 | LMNA (0.42) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL8490114 | 0.85 | LMNA (0.63) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL29195737 | 0.85 | LMNA (0.63) | MAPTMAPK1LMNAPRKCAPRKCE | |
| SCHEMBL2136744 | 0.85 | LMNA (0.63) | MAPTMAPK1LMNAPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350924-B1 | Method for producing 1,4-butanediol | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-26 | — | — | US | disclosed |