Ethylene Glycol

Ethylene Glycol

SCHEMBL4914065

CCCC(O)OC(=O)CCCCC(=O)O.OCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.46
FFAR1 O14842 2/20 0.46
ALDH1A1 P00352 3/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
AKR1B1 P15121 1/20 0.44
LMNA P02545 2/20 0.43
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
HDAC11 Q96DB2 5/20 0.42
TSHR P16473 4/20 0.42
PTPN1 P18031 3/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114259 0.95 FFAR4 (0.50) FFAR4FFAR1ALDH1A1MAPTMAPK1
SCHEMBL5475791 0.93 FFAR4 (0.53) FFAR4FFAR1ALDH1A1MAPTMAPK1
SCHEMBL8153854 0.91 TSHR (0.48) FFAR4FFAR1ALDH1A1AKR1B1LMNA
Alanine SCHEMBL5177390 0.89 ALDH1A1 (0.49) FFAR4FFAR1ALDH1A1AKR1B1LMNA
Adipic Acid SCHEMBL437560 0.88 FFAR4 (0.47) FFAR4FFAR1ALDH1A1AKR1B1LMNA
SCHEMBL11652184 0.88 LMNA (0.53) ALDH1A1MAPTMAPK1LMNATSHR
SCHEMBL1592728 0.86 MAPT (0.51) ALDH1A1MAPTMAPK1LMNAMEN1
SCHEMBL7725819 0.86 MAPT (0.46) ALDH1A1MAPTMAPK1LMNATSHR
SCHEMBL6284823 0.86 FFAR4 (0.54) FFAR4FFAR1ALDH1A1MAPTMAPK1
SCHEMBL630306 0.85 FFAR4 (0.61) FFAR4FFAR1ALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080193990-A1 Tow-Step Method for Producing Polyesterols BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-6699957-B2 REACTION PRODUCT OF AN ALIPHATIC DIISOCYANATE MONOMER, HIGH MOLECULAR WEIGHT POLYOL, A LOW MOLECULAR WEIGHT AROMATIC DIOL AND A SATURATED DIOL CURING AGENT UNIROYAL CHEMICAL COMPANY, INC. 2004-03-02 US disclosed
US-20030149215-A1 Resilient, shear resistant polyurethane compositions for golf ball covers UNIROYAL CHEMICAL COMPANY, INC 2003-08-07 US disclosed
US-6530849-B2 Copolymer of toluene-2,4- or 2,6-diisocyanate, low molecular weight polyoxypropylene glycol and diamine functional chain extender; high resilience and shear resistance UNIROYAL CHEMICAL COMPANY, INC. 2003-03-11 US disclosed
WO-2002064658-A1 LOW COST, RESILIENT, SHEAR RESISTANT POLYURETHANE ELASTOMERS FOR GOLF BALL COVERS UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-08-22 WO disclosed
US-20020049099-A1 Low cost, resilient, shear resistant polyurethane elastomers for golf ball covers UNIROYAL CHEMICAL COMPANY, INC. 2002-04-25 US disclosed
US-6309313-B1 AN INEXPENSIVE COVER OF A POLYETHERURETHANE COPOLYMER CHAIN EXTENDED BY A DIAMINE OR DIHYDROXY COMPOUND; POLYETHER MONOMER COMPRISING ETHYLENE GLYCOL OR ETHYLENE GLYCOL AND PROPYLENE GLYCOL; COLORFASTNESS; PHOTOSTABILITY UNIROYAL CHEMICAL COMPANY, INC. 2001-10-30 US disclosed
EP-0941264-B1 ADHESIVE COMPOUNDING INGREDIENTS LTD (GB) 2001-07-11 EP disclosed
EP-0941264-A1 ADHESIVE Compounding Ingredients Limited (GB) 1999-09-15 EP disclosed
WO-1998023660-A1 ADHESIVE COMPOUNDING INGREDIENTS LIMITED (GB) 1998-06-04 WO disclosed
US-5599874-A HYDRAULIC SEALS; WEAR RESISTANCE, PRESSURE RESISTANCE CATERPILLAR INC. (US) 1997-02-04 US disclosed