Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | CA2 | P00918 | 6/20 | 0.77 |
| ▸ | HPGD | P15428 | 4/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.77 |
| ▸ | CA4 | P22748 | 4/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | CA12 | O43570 | 3/20 | 0.77 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.77 |
| ▸ | EGFR | P00533 | 2/20 | 0.77 |
| ▸ | FYN | P06241 | 2/20 | 0.77 |
| ▸ | MMP9 | P14780 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | CA3 | P07451 | 2/20 | 0.77 |
| ▸ | GMNN | O75496 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL9239332 | 1.00 | ALDH1A1 (0.77) | ALDH1A1CA2HPGDTDP1CA4 | |
| Catechol SCHEMBL18351 | 0.88 | — | — | |
| Catechol SCHEMBL29352716 | 0.88 | — | — | |
| Catechol SCHEMBL30944695 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CA2HPGDTDP1CA4 | |
| Catechol SCHEMBL367675 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CA2HPGDTDP1CA4 | |
| Catechol SCHEMBL11672589 | 0.88 | ALDH1A1 (1.00) | ALDH1A1CA2HPGDTDP1CA4 | |
| Catechol SCHEMBL30088487 | 0.88 | — | — | |
| Catechol SCHEMBL10938013 | 0.86 | ALDH1A1 (0.67) | ALDH1A1CA2HPGDTDP1CA4 | |
| Catechol SCHEMBL10937188 | 0.86 | ALDH1A1 (0.67) | ALDH1A1CA2HPGDTDP1CA4 | |
| Catechol SCHEMBL7060022 | 0.86 | ALDH1A1 (0.67) | ALDH1A1CA2HPGDTDP1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395894-B2 | BACTERICIDES | MERCK & CO., INC. | 2002-05-28 | — | — | US | claimed |
| US-20010025103-A1 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS PRODUCED | MERCK & CO., INC. | 2001-09-27 | — | — | US | claimed |
| EP-1071685-A4 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | MERCK & CO INC (US) | 2001-07-18 | — | — | EP | claimed |
| EP-1071685-A1 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | Merck & Co., Inc. (US) | 2001-01-31 | — | — | EP | claimed |
| WO-1999052908-A1 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | MERCK & CO., INC. (US) | 1999-10-21 | — | — | WO | claimed |
| EP-0211236-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-25 | — | — | EP | claimed |
| CN-104119376-A | Synthesis method of chlorinated pyrocatechol phosphite | LIU QIN | 2014-10-29 | — | — | CN | disclosed |
| CN-104119376-A | Synthesis method of chlorinated pyrocatechol phosphite | LIU QIN | 2014-10-29 | — | — | CN | disclosed |
| US-6395894-B2 | BACTERICIDES | MERCK & CO., INC. | 2002-05-28 | — | — | US | disclosed |
| US-20010025103-A1 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS PRODUCED | MERCK & CO., INC. | 2001-09-27 | — | — | US | disclosed |
| EP-1071685-A4 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | MERCK & CO INC (US) | 2001-07-18 | — | — | EP | disclosed |
| EP-1071685-A1 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | Merck & Co., Inc. (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999052908-A1 | TITANIUM CATALYZED PREPARATION OF CARBAPENEM INTERMEDIATES | MERCK & CO., INC. (US) | 1999-10-21 | — | — | WO | disclosed |
| EP-0212404-A1 | 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| EP-0211236-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-25 | — | — | EP | disclosed |
| EP-0058317-B1 | PROCESS FOR THE PREPARATION OF 2-PENEM COMPOUNDS | SCHERING CORPORATION (US) | 1986-08-27 | — | — | EP | disclosed |
| US-4495320-A | 3,6-Di-t-butyl-2-naphthyl catechol phosphite and compositions thereof | THE B. F. GOODRICH COMPANY (US) | 1985-01-22 | — | — | US | disclosed |
| EP-0102239-A1 | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY LIMITED (JP) | 1984-03-07 | — | — | EP | disclosed |
| US-4416829-A | OXIDATION AND CORROSION RESISTANCE TO LUBRICANT OILS | STANDARD OIL COMPANY (INDIANA) (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0058317-A1 | Process for the preparation of 2-penem compounds | SCHERING CORPORATION (US) | 1982-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025103-A1 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES, AND COMPOUNDS PRODUCED | HAAO, HACL2, HAO2 | ALDH1A1 883/4885CA2 2735/4885HPGD 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.