Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.67 |
| ▸ | GRM6 | O15303 | 2/20 | 0.67 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.67 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.67 |
| ▸ | GLUL | P15104 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.58 |
| ▸ | GCLC | P48506 | 1/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamic Acid SCHEMBL6861840 | 0.87 | GRM8 (0.69) | GRM8GRM6GRM7GRM4GLUL | |
| D-Glutamate SCHEMBL6861834 | 0.87 | GRM8 (0.69) | GRM8GRM6GRM7GRM4GLUL | |
| Glufosinate SCHEMBL4015717 | 0.87 | GRM8 (0.63) | GRM8GRM6GRM7GRM4GLUL | |
| Methyl Alcohol SCHEMBL28474438 | 0.85 | GLUL (0.66) | GRM8GRM6GRM7GRM4GLUL | |
| SCHEMBL1969235 | 0.85 | GLUL (0.70) | GRM8GRM6GRM7GRM4GLUL | |
| SCHEMBL31230376 | 0.85 | GLUL (0.70) | GRM8GRM6GRM7GRM4GLUL | |
| SCHEMBL56139 | 0.85 | GLUL (0.70) | GRM8GRM6GRM7GRM4GLUL | |
| SCHEMBL12648443 | 0.85 | GLUL (0.70) | GRM8GRM6GRM7GRM4GLUL | |
| Water SCHEMBL21747433 | 0.83 | GLUL (0.68) | GRM8GRM6GRM7GRM4GLUL | |
| Water SCHEMBL21747432 | 0.83 | GLUL (0.68) | GRM8GRM6GRM7GRM4GLUL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015479-A4 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1015479-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |