Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12317970 | 0.84 | ALDH1A1 (0.65) | ERN1MAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL29496942 | 0.84 | ALDH1A1 (0.65) | ERN1MAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL21289970 | 0.83 | DYRK1A (0.55) | ERN1MAPTALDH1A1NPC1LMNA | |
| SCHEMBL27539112 | 0.83 | ERN1 (0.74) | ERN1MAPTALDH1A1NPC1LMNA | |
| SCHEMBL29496946 | 0.81 | MEN1 (0.56) | ERN1MAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5797361 | 0.81 | MEN1 (0.56) | ERN1MAPTALDH1A1NPC1SMN1; SMN2 | |
| Formaldehyde SCHEMBL28904788 | 0.80 | ALDH1A1 (0.60) | ERN1MAPTALDH1A1NPC1LMNA | |
| SCHEMBL29901547 | 0.80 | KMO (0.53) | ERN1MAPTALDH1A1NPC1LMNA | |
| SCHEMBL31432885 | 0.79 | ERN1 (0.53) | ERN1MAPTALDH1A1NPC1LMNA | |
| Formaldehyde SCHEMBL28904777 | 0.77 | ERN1 (0.55) | ERN1MAPTALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395753-B1 | ANTIHISTAMINES, ANTIALLERGENS, ANTIARTHRITIC AGENTS | KOWA CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |