Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730048 | 0.89 | PLCG1 (0.36) | PLCG1ALDH1A1ELANE | |
| SCHEMBL7728210 | 0.89 | PLCG1 (0.33) | PLCG1 | |
| SCHEMBL7722500 | 0.88 | PLCG1 (0.37) | PLCG1ALDH1A1ELANE | |
| SCHEMBL7722214 | 0.88 | PLCG1 (0.37) | PLCG1ALDH1A1ELANE | |
| SCHEMBL7728733 | 0.88 | ALDH1A1 (0.34) | PLCG1ALDH1A1ELANE | |
| SCHEMBL8196175 | 0.88 | PLCG1 (0.38) | PLCG1ALDH1A1ELANE | |
| SCHEMBL7722332 | 0.88 | PLCG1 (0.37) | PLCG1ALDH1A1ELANE | |
| SCHEMBL7728195 | 0.87 | ALDH1A1 (0.40) | PLCG1ALDH1A1ELANE | |
| SCHEMBL7728648 | 0.87 | PLCG1 (0.37) | PLCG1ALDH1A1ELANE | |
| SCHEMBL7729308 | 0.85 | PLCG1 (0.36) | PLCG1ALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |