Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730470 | 1.00 | FAP (0.32) | FAPALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL7728252 | 0.86 | FAP (0.34) | FAP | |
| SCHEMBL7634484 | 0.85 | CYP19A1 (0.34) | FAPALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL7722337 | 0.83 | FAP (0.35) | FAP | |
| SCHEMBL7731772 | 0.82 | FAP (0.33) | FAP | |
| SCHEMBL7722505 | 0.82 | FAP (0.31) | FAP | |
| SCHEMBL7729417 | 0.81 | FAP (0.34) | FAP | |
| SCHEMBL7722242 | 0.81 | FAP (0.34) | FAP | |
| SCHEMBL7729901 | 0.81 | FAP (0.34) | FAP | |
| SCHEMBL7734763 | 0.80 | FAP (0.34) | FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |