Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.59 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581155 | 0.90 | CES2 (0.53) | CES2MAPTMAPK1 | |
| SCHEMBL3424705 | 0.90 | CES2 (0.53) | CES2MAPTMAPK1 | |
| SCHEMBL10525399 | 0.90 | CES2 (0.53) | CES2MAPTMAPK1 | |
| SCHEMBL9354071 | 0.90 | CES2 (0.53) | CES2MAPTMAPK1 | |
| SCHEMBL28560976 | 0.90 | CES2 (0.53) | CES2MAPTMAPK1 | |
| SCHEMBL844234 | 0.88 | CES2 (0.61) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL10414287 | 0.87 | CES2 (0.50) | CES2CES1MAPTMAPK1 | |
| SCHEMBL9390983 | 0.86 | CES2 (0.50) | CES2CES1MAPTMAPK1 | |
| SCHEMBL7797219 | 0.86 | CES2 (0.50) | CES2CES1MAPTMAPK1 | |
| SCHEMBL9806356 | 0.82 | CES2 (0.59) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410597-B1 | ANTIINFLAMMATORY AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2002-06-25 | — | — | US | disclosed |