Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797219 | 1.00 | CES2 (0.50) | CES2MAPTKMT2AMAPK1PIK3R1 | |
| SCHEMBL2999181 | 0.87 | CES2 (0.52) | CES2MAPTKMT2AMAPK1PIK3R1 | |
| SCHEMBL7728962 | 0.86 | CES2 (0.59) | CES2MAPTMAPK1CES1 | |
| SCHEMBL28213314 | 0.85 | CES2 (0.50) | CES2MAPTKMT2AMAPK1PIK3R1 | |
| SCHEMBL2993421 | 0.85 | CES2 (0.50) | CES2MAPTKMT2AMAPK1PIK3R1 | |
| SCHEMBL29283927 | 0.84 | CES2 (0.48) | CES2MAPTKMT2AMAPK1PIK3R1 | |
| SCHEMBL29255787 | 0.84 | CES2 (0.48) | CES2MAPTKMT2AMAPK1PIK3R1 | |
| SCHEMBL932701 | 0.84 | KMT2A (0.55) | CES2MAPTKMT2AMEN1 | |
| SCHEMBL999329 | 0.84 | CES2 (0.48) | CES2MAPTKMT2APIK3R1AKT1 | |
| SCHEMBL3424705 | 0.81 | CES2 (0.53) | CES2MAPTKMT2AMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994019309-A1 | A NOVEL METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE COMPOUNDS AS WELL AS NOVEL END PRODUCTS | MAEENSIVU EIJA (FI) | 1994-09-01 | — | — | WO | disclosed |