Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 7/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | CPA2 | P48052 | 1/20 | 0.40 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.39 |
| ▸ | BMP1 | P13497 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736469 | 0.88 | CTSS (0.37) | SIRT5BACE1GNPATCPA1CPA2 | |
| SCHEMBL17424544 | 0.87 | BACE1 (0.46) | SIRT5BACE1GNPATCPA1CPA2 | |
| SCHEMBL29695567 | 0.87 | GNPAT (0.47) | SIRT5BACE1GNPATCPA1CPA2 | |
| SCHEMBL6534663 | 0.86 | GNPAT (0.54) | BACE1GNPATCASP1CASP3CASP7 | |
| SCHEMBL7166591 | 0.86 | GNPAT (0.48) | SIRT5BACE1GNPATCASP1CASP3 | |
| SCHEMBL20614482 | 0.85 | CPA1 (0.43) | SIRT5BACE1GNPATCPA1CPA2 | |
| SCHEMBL16507903 | 0.85 | BACE1 (0.45) | SIRT5BACE1CASP1BACE2BMP1 | |
| SCHEMBL22310788 | 0.85 | GNPAT (0.47) | BACE1GNPATCASP1CASP3CASP7 | |
| SCHEMBL29802309 | 0.82 | FOLH1 (0.53) | BACE1GNPATBACE2FOLH1 | |
| SCHEMBL31634368 | 0.82 | KDM4E (0.51) | BACE1GNPATCASP1CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |
| US-6800434-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2004-10-05 | — | — | US | disclosed |