Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.46 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | CPA2 | P48052 | 1/20 | 0.41 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695567 | 0.94 | GNPAT (0.47) | BACE1GNPATCTSDFOLH1NAALAD2 | |
| SCHEMBL16199305 | 0.90 | FOLH1 (0.42) | BACE1BACE2CTSDFOLH1NAALAD2 | |
| SCHEMBL29802309 | 0.89 | FOLH1 (0.53) | BACE1BACE2GNPATFOLH1NAALAD2 | |
| SCHEMBL6534663 | 0.87 | GNPAT (0.54) | BACE1BACE2GNPATCTSDCASP1 | |
| SCHEMBL7729169 | 0.87 | SIRT5 (0.42) | BACE1BACE2GNPATCTSDFOLH1 | |
| SCHEMBL16199302 | 0.86 | BACE1 (0.42) | BACE1CTSDFOLH1NAALAD2RIMKLA | |
| SCHEMBL30483835 | 0.86 | BACE1 (0.54) | BACE1BACE2CTSD | |
| SCHEMBL7735460 | 0.85 | ALDH1A1 (0.42) | BACE1GNPATCTSDCPA1CPA2 | |
| SCHEMBL7166591 | 0.85 | GNPAT (0.48) | BACE1BACE2GNPATCASP1CASP3 | |
| SCHEMBL2628233 | 0.84 | BACE1 (0.44) | BACE1BACE2CTSDFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234003-B2 | Palladium catalyzed reactions executed on solid-phase peptide synthesis supports for the production of self-assembling peptides embedded with complex organic electronic subunits | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-01-12 | — | — | US | disclosed |