SCHEMBL7729245

SCHEMBL7729245

CCOC(=O)C=Cc1cc(N2C(=O)c3ccccc3C2=O)c(F)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 2/20 0.39
CCNC P24863 1/20 0.39
CDK8 P49336 1/20 0.39
PKM P14618 1/20 0.39
PPOX P50336 2/20 0.39
NPC1 O15118 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
GRM1 Q13255 2/20 0.39
P2RX3 P56373 1/20 0.39
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7729242 1.00 MEN1 (0.41) MEN1KMT2ACYP3A4CCNCCDK8
SCHEMBL11035594 0.84 PPOX (0.43) PPOX
SCHEMBL8942320 0.76 CYP3A4 (0.47) CYP3A4CCNCCDK8PKMLMNA
SCHEMBL8942315 0.76 CYP3A4 (0.47) CYP3A4CCNCCDK8PKMLMNA
SCHEMBL7729726 0.75 PPOX (0.42) MEN1KMT2APPOXGRM1LMNA
SCHEMBL9796720 0.75 PKM (0.38) CYP3A4CCNCCDK8PKMPPOX
SCHEMBL9797096 0.75 PKM (0.38) CYP3A4CCNCCDK8PKMPPOX
SCHEMBL9796782 0.74 CNKSR1 (0.46) CYP3A4CCNCCDK8PKMP2RX3
SCHEMBL9796785 0.74 CNKSR1 (0.46) CYP3A4CCNCCDK8PKMP2RX3
SCHEMBL8649070 0.73 PPOX (0.42) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6365753-B1 EXCELLENT PREFERENTIAL EFFECTS ON WEEDS; GRASSES; NONPHYTOTOXIC TO CROPS E.G. WHEAT; BARLEY; CORN MITSUBISHI CHEMICAL CORPORATION (JP) 2002-04-02 US disclosed
EP-1097923-A1 PHTHALIMIDES AND HERBICIDE CONTAINING THE SAME AS ACTIVE COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2001-05-09 EP disclosed