Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722737 | 0.97 | TSHR (0.45) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7730680 | 0.93 | MEN1 (0.37) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7735367 | 0.92 | TSHR (0.35) | TSHRHSD17B10GRM2PPARGPPARA | |
| SCHEMBL12623096 | 0.91 | RARB (0.43) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7734975 | 0.91 | TSHR (0.34) | TSHRHSD17B10PPARGPPARAS1PR1 | |
| SCHEMBL12623092 | 0.89 | RARB (0.41) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7730801 | 0.89 | HSD17B10 (0.39) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7731469 | 0.89 | PPARA (0.34) | PPARGPPARAPPARD | |
| SCHEMBL7730411 | 0.88 | HSD17B10 (0.39) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7732832 | 0.87 | KIF11 (0.36) | TSHRHSD17B10RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |