Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730801 | 0.96 | HSD17B10 (0.39) | TSHRHSD17B10ALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL7734975 | 0.94 | TSHR (0.34) | TSHRHSD17B10S1PR1S1PR3NPC1 | |
| SCHEMBL7733192 | 0.93 | ALPL (0.34) | ALDH1A1HPGDNPSR1SENP8SENP7 | |
| SCHEMBL7729299 | 0.92 | TSHR (0.40) | TSHRHSD17B10S1PR1ALDH1A1PSEN1 | |
| SCHEMBL7732803 | 0.91 | S1PR1 (0.31) | S1PR1S1PR3PCSK9 | |
| SCHEMBL7731080 | 0.91 | — | — | |
| SCHEMBL7730411 | 0.91 | HSD17B10 (0.39) | TSHRHSD17B10S1PR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7722737 | 0.89 | TSHR (0.45) | TSHRHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7729948 | 0.88 | S1PR1 (0.33) | TSHRHSD17B10S1PR1PPARGPPARA | |
| SCHEMBL7729908 | 0.88 | TSHR (0.32) | TSHRHSD17B10S1PR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |