Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729472 | 1.00 | AGTR2 (0.36) | AGTR2BTKSMN1; SMN2MMP2ANPEP | |
| SCHEMBL7733245 | 0.90 | MMP2 (0.38) | MMP2ANPEPCYP1A2POLBCYP3A4 | |
| SCHEMBL7733241 | 0.90 | MMP2 (0.38) | MMP2ANPEPCYP1A2POLBCYP3A4 | |
| SCHEMBL7727152 | 0.90 | AGTR2 (0.38) | AGTR2BTKSMN1; SMN2MMP2ANPEP | |
| SCHEMBL7727155 | 0.90 | AGTR2 (0.38) | AGTR2BTKSMN1; SMN2MMP2ANPEP | |
| SCHEMBL7727788 | 0.82 | BTK (0.44) | AGTR2BTKMMP2ANPEPTLR2 | |
| SCHEMBL7727791 | 0.82 | BTK (0.44) | AGTR2BTKMMP2ANPEPTLR2 | |
| SCHEMBL10594861 | 0.80 | BTK (0.41) | AGTR2BTKSMN1; SMN2MMP2ANPEP | |
| SCHEMBL10594866 | 0.80 | BTK (0.41) | AGTR2BTKSMN1; SMN2MMP2ANPEP | |
| SCHEMBL7727967 | 0.79 | BTK (0.40) | AGTR2BTKSMN1; SMN2MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |