Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729568 | 1.00 | CCR1 (0.60) | CCR1SIGMAR1AGTR2SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL7729520 | 0.98 | CCR1 (0.58) | CCR1SIGMAR1AGTR2SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL7729513 | 0.98 | CCR1 (0.58) | CCR1SIGMAR1AGTR2SLC6A2SLC6A3 | |
| SCHEMBL7242922 | 0.94 | SIGMAR1 (0.68) | CCR1SIGMAR1AGTR2SLC6A2SLC6A3 | |
| SCHEMBL19049037 | 0.93 | CCR1 (0.55) | CCR1SIGMAR1AGTR2SLC6A2SLC6A3 | |
| SCHEMBL7723974 | 0.84 | SIGMAR1 (0.53) | CCR1SIGMAR1C3AR1HTR2ADRD4 | |
| SCHEMBL7723985 | 0.84 | SIGMAR1 (0.53) | CCR1SIGMAR1C3AR1HTR2ADRD4 | |
| SCHEMBL7240225 | 0.83 | SIGMAR1 (0.58) | CCR1SIGMAR1DRD4 | |
| SCHEMBL7719838 | 0.83 | SIGMAR1 (0.57) | CCR1SIGMAR1C3AR1HTR2AKDM4E | |
| SCHEMBL7719831 | 0.83 | SIGMAR1 (0.57) | CCR1SIGMAR1C3AR1HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |