Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723974 | 1.00 | SIGMAR1 (0.53) | SIGMAR1DRD4DRD2DRD3LTA4H | |
| SCHEMBL7729521 | 0.92 | DRD2 (0.45) | SIGMAR1DRD4DRD2HTR2A | |
| SCHEMBL7729514 | 0.92 | DRD2 (0.45) | SIGMAR1DRD4DRD2HTR2A | |
| SCHEMBL7729568 | 0.84 | CCR1 (0.60) | SIGMAR1DRD4LTA4HCXCR3C3AR1 | |
| SCHEMBL7729558 | 0.84 | CCR1 (0.60) | SIGMAR1DRD4LTA4HCXCR3C3AR1 | |
| Oxalic Acid SCHEMBL7729513 | 0.82 | CCR1 (0.58) | SIGMAR1DRD4CXCR3C3AR1HTR2A | |
| Oxalic Acid SCHEMBL7729520 | 0.82 | CCR1 (0.58) | SIGMAR1DRD4CXCR3C3AR1HTR2A | |
| SCHEMBL11841818 | 0.82 | CYP1A2 (0.50) | SIGMAR1DRD4DRD2DRD3C3AR1 | |
| SCHEMBL7242922 | 0.78 | SIGMAR1 (0.68) | SIGMAR1DRD4CXCR3C3AR1HTR2A | |
| SCHEMBL11834924 | 0.78 | CCR1 (0.47) | C3AR1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |