SCHEMBL7729908

SCHEMBL7729908

CCCCCc1cc(F)c(C(F)(F)Oc2ccc(C(F)(F)Oc3cc(F)c(C#N)c(F)c3)cc2)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
S1PR1 P21453 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7731080 0.97
SCHEMBL7732804 0.92 AR (0.31)
SCHEMBL7730801 0.91 HSD17B10 (0.39) TSHRHSD17B10THRB
SCHEMBL7730411 0.90 HSD17B10 (0.39) TSHRHSD17B10S1PR1THRB
SCHEMBL7722550 0.90 HSD17B10 (0.39) TSHRHSD17B10S1PR1THRB
SCHEMBL7735394 0.88 TSHR (0.40) TSHRHSD17B10S1PR1THRB
SCHEMBL7729257 0.88 THRB (0.33) S1PR1THRB
SCHEMBL7735367 0.88 TSHR (0.35) TSHRHSD17B10S1PR1THRB
SCHEMBL7731547 0.88 DHODH (0.31)
SCHEMBL7730819 0.88 THRB (0.33) S1PR1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed