SCHEMBL7729923

SCHEMBL7729923

CCCc1ccc(C(F)(F)Oc2ccc(-c3cc(F)c(OC(F)F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.34
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
FFAR1 O14842 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7731609 0.94 RARB (0.34) KIF11CYP11B1CYP11B2
SCHEMBL7730726 0.93 RARB (0.38) KIF11CYP11B1CYP11B2
SCHEMBL7723050 0.91 KIF11 (0.36) KIF11CYP11B1CYP11B2FFAR1
SCHEMBL7733489 0.91 CETP (0.32) FFAR1
SCHEMBL7732942 0.90 FFAR1 (0.31) FFAR1
SCHEMBL7731837 0.88 FFAR1 (0.30) FFAR1
SCHEMBL7730937 0.88 CYP11B1 (0.37) KIF11CYP11B1CYP11B2
SCHEMBL7722507 0.87 FFAR4 (0.31)
SCHEMBL7731674 0.87 MAOB (0.33) CNR2
SCHEMBL7732570 0.86 KIF11 (0.39) KIF11CYP11B1CYP11B2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed