SCHEMBL7733489

SCHEMBL7733489

CCCc1ccc(C(F)(F)Oc2ccc(CCc3cc(F)c(OC(F)F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.32
DAO P14920 2/20 0.32
FFAR1 O14842 1/20 0.31
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7735352 0.93 CETP (0.34) CETPDAOFFAR1BACE1
SCHEMBL7731573 0.92 S1PR1 (0.34) CETPBACE1
SCHEMBL7729345 0.92 FFAR4 (0.32) DAOFFAR1
SCHEMBL7732942 0.92 FFAR1 (0.31) CETPDAOFFAR1
SCHEMBL7729923 0.91 KIF11 (0.34) FFAR1
SCHEMBL7731837 0.90 FFAR1 (0.30) FFAR1
SCHEMBL7735193 0.88 CETP (0.33) CETPDAO
SCHEMBL7730527 0.88 CETP (0.33) CETPDAO
SCHEMBL7728636 0.87 DAO (0.36) DAOBACE1
SCHEMBL7729833 0.86 DAO (0.34) DAOFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed