⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679242 | 0.97 | ADH1A (1.00) | — | |
| SCHEMBL772457 | 0.97 | ADH1A (1.00) | — | |
| SCHEMBL1678872 | 0.97 | ADH1A (1.00) | — | |
| SCHEMBL967159 | 0.97 | — | — | |
| SCHEMBL308431 | 0.88 | — | — | |
| Ethyne SCHEMBL20506470 | 0.83 | — | — | |
| Bicarbonate SCHEMBL10721946 | 0.79 | ADH1A (0.62) | — | |
| SCHEMBL13744423 | 0.79 | ADH1A (0.62) | — | |
| SCHEMBL24230521 | 0.77 | ADH1A (0.60) | — | |
| SCHEMBL1569623 | 0.77 | ADH1A (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918940-B | Purine inhibitors of human phosphatidylinositol 3-kinase | 默沙东公司 | 2017-03-08 | — | — | CN | claimed |
| EP-1906945-B1 | HCV INHIBITORS | VIROBAY INC (US) | 2015-08-05 | — | — | EP | claimed |
| US-20250214960-A1 | COMPOUNDS HAVING ACTIVITY OF DEGRADING GSPT1 AND APPLICATION THEREOF | SHANGHAI BIOPARTNERSX CO., LTD. (CN) | 2025-07-03 | — | — | US | disclosed |
| WO-2023078410-A1 | COMPOUND HAVING ACTIVITY OF DEGRADING GSPT1 AND APPLICATION THEREOF | 上海美志医药科技有限公司 | 2023-05-11 | — | — | WO | disclosed |
| WO-2020029846-A1 | RAPID SYNTHESIS METHOD FOR BIOMASS-BASED AMINE COMPOUND | 南京农业大学 | 2020-02-13 | — | — | WO | disclosed |
| CN-109310695-A | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | 阿斯特罗赛特制药公司 | 2019-02-05 | — | — | CN | disclosed |
| EP-2318355-B1 | 1,1'-DIADAMANTYL CARBOXYLIC ACIDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2018-09-12 | — | — | EP | disclosed |
| CN-104918940-B | Purine inhibitors of human phosphatidylinositol 3-kinase | 默沙东公司 | 2017-03-08 | — | — | CN | disclosed |
| US-9408392-B2 | Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-09 | — | — | US | disclosed |
| EP-2831046-B1 | N-CYCLYLAMIDES AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| EP-2627631-B1 | PYRROLIDINONES AS METAP2 INHIBITORS | MERCK PATENT GMBH (DE) | 2015-12-16 | — | — | EP | disclosed |
| US-20060167246-A1 | Thienopyrrole compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20010001101-A1 | Phenanthroline derivatives | ZENECA LIMITED | 2001-05-10 | — | — | US | disclosed |
| US-5916898-A | ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5224987-A | Aqueous carriers with colors and tertiary amide penetrants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0517262-A1 | Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5084449-A | Bactericides and antiprotozoa agents | DR. KARL THOMAE GMBH (DE) | 1992-01-28 | — | — | US | disclosed |
| US-4992430-A | Anti-bacterial compositions comprising a substituted bis-(4-aminophenyl)-sulfone and a dihydro-folic acid reductase | DR. KARL THOMAE GMBH (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4829058-A | INHIBITORS OF BACTERIA, MYCOBACTERIA AND PLASMODIA | DR. KARL THOMAE GMBH (DE) | 1989-05-09 | — | — | US | disclosed |