Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 12/20 | 1.00 |
| ▸ | ADH1C | P00326 | 9/20 | 1.00 |
| ▸ | ADH1B | P00325 | 3/20 | 0.52 |
| ▸ | ADH4 | P08319 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678872 | 1.00 | ADH1A (1.00) | ADH1AADH1CADH1BADH4FAAH | |
| SCHEMBL1679242 | 1.00 | ADH1A (1.00) | ADH1AADH1CADH1BADH4FAAH | |
| SCHEMBL772996 | 0.97 | — | — | |
| SCHEMBL967159 | 0.95 | — | — | |
| SCHEMBL308431 | 0.86 | — | — | |
| Ethyne SCHEMBL20506470 | 0.81 | — | — | |
| Bicarbonate SCHEMBL10721946 | 0.77 | ADH1A (0.62) | ADH1AADH1CADH1BADH4TSHR | |
| SCHEMBL13744423 | 0.77 | ADH1A (0.62) | ADH1AADH1CADH1BADH4TSHR | |
| SCHEMBL24230521 | 0.75 | ADH1A (0.60) | ADH1AADH1CADH1BADH4TSHR | |
| SCHEMBL1569623 | 0.75 | ADH1A (0.60) | ADH1AADH1CADH1BADH4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1906945-B1 | HCV INHIBITORS | VIROBAY INC (US) | 2015-08-05 | — | — | EP | claimed |
| US-7553850-B2 | Tricyclic-bridged piperidinylidene derivatives as δ-opioid modulators | JANSSEN PHARMACEUTICA NV (BG) | 2009-06-30 | — | — | US | claimed |
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | claimed |
| US-20080275066-A1 | Condensed Thiophene Derivatives and Their Use as Cyclic Glp-1 Agonists | NOVO NORDISK A/S (DK) | 2008-11-06 | — | — | US | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | US | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| EP-1765814-A1 | CONDENSED THIOPHENE DERIVATIVES AND THEIR USE AS CYCLIC GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2007-03-28 | — | — | EP | claimed |
| CN-1918101-A | Processes for preparing benzoquinones and hydroquinones | GEN ELECTRIC (US) | 2007-02-21 | — | — | CN | claimed |
| EP-1718653-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | Ligand Pharmaceuticals Inc. (US) | 2006-11-08 | — | — | EP | claimed |
| EP-0230224-B1 | PROCESS FOR THE PREPARATION OF ALCOXYCARBONYL ISOCYANATES | BAYER AG (DE) | 1991-07-17 | — | — | EP | claimed |
| EP-0152759-B1 | AMINOISOTHIAZOLE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1989-08-23 | — | — | EP | claimed |
| EP-0150034-B1 | DERIVATIVES OF 2-AMINOTHIOPHENE | BASF Aktiengesellschaft (DE) | 1989-08-02 | — | — | EP | claimed |
| US-4785116-A | Aminoisothiazole compounds | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | claimed |
| US-4777283-A | Process for the preparation of alkoxycarbonyl isocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-11 | — | — | US | claimed |
| EP-0165422-B1 | SUBSTITUTED BIS-(4-AMINOPHENYL)-SULPHONES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1988-03-09 | — | — | EP | claimed |
| EP-0230224-A2 | Process for the preparation of alcoxycarbonyl isocyanates | BAYER AG (DE) | 1987-07-29 | — | — | EP | claimed |
| EP-0026000-B1 | SPIRO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1983-05-11 | — | — | EP | claimed |
| US-4362740-A | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-12-07 | — | — | US | claimed |
| EP-0026000-A1 | Spiro compounds, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | NR3C1, NR3C2, MC2R | ADH1A 661/4885ADH1C 941/4885ADH1B 910/4885 |
| US-20080275066-A1 | Condensed Thiophene Derivatives and Their Use as Cyclic Glp-1 Agonists | GLP1R, GIPR, GCGR | ADH1A 3058/4885ADH1C 2262/4885ADH1B 4575/4885 |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | NR3C1, NR3C2, MC2R | ADH1A 661/4885ADH1C 941/4885ADH1B 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.