Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729967 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7730515 | 0.97 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7730528 | 0.97 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7730520 | 0.97 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7731204 | 0.94 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7731207 | 0.94 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL12032302 | 0.93 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7730689 | 0.93 | MAPT (0.34) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7730695 | 0.93 | MAPT (0.34) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7735095 | 0.92 | KDM1A (0.36) | ALDH1A1LMNAMAPTCYP2C9KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786508-B1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | CHISSO CORP (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5728319-A | Liquid crystal composition and liquid crystal display device | CHISSO CORPORATION (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0786508-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |