SCHEMBL7730528

SCHEMBL7730528

CCC[C@H]1CC[C@H]([C@H]2CC[C@H](c3ccc(C(F)(F)Oc4ccc(C(F)(F)F)c(F)c4)cc3)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.38
MEN1 O00255 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM1A O60341 1/20 0.33
HTR2C P28335 1/20 0.30
PDE2A O00408 1/20 0.30
CHRNA7 P36544 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7730520 1.00 ALDH1A1 (0.39) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730515 1.00 ALDH1A1 (0.39) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7729967 0.97 ALDH1A1 (0.41) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7729964 0.97 ALDH1A1 (0.41) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL12032302 0.96 ALDH1A1 (0.36) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7722931 0.94 ALDH1A1 (0.33) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7722924 0.94 ALDH1A1 (0.33) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7722929 0.94 ALDH1A1 (0.33) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730489 0.93 ALDH1A1 (0.33) ALDH1A1LMNAMAPTCYP2C9MEN1
SCHEMBL7730480 0.93 ALDH1A1 (0.33) ALDH1A1LMNAMAPTCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed