Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 10/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729932 | 0.88 | PLCG1 (0.37) | PLCG1ELANETDP1 | |
| SCHEMBL7722253 | 0.88 | PLCG1 (0.36) | PLCG1ELANETDP1 | |
| SCHEMBL7722452 | 0.84 | PLCG1 (0.34) | PLCG1ELANE | |
| SCHEMBL6894060 | 0.82 | IDO1 (0.40) | IDO1TDO2 | |
| SCHEMBL7722543 | 0.82 | IDO1 (0.38) | IDO1TDO2 | |
| SCHEMBL7722709 | 0.78 | PLCG1 (0.38) | PLCG1ELANE | |
| SCHEMBL8195457 | 0.77 | PLCG1 (0.38) | PLCG1ELANEIDO1TDO2 | |
| SCHEMBL7729339 | 0.77 | PLCG1 (0.40) | PLCG1ELANETDP1ATM | |
| SCHEMBL7729933 | 0.76 | L3MBTL1 (0.40) | PLCG1ELANE | |
| SCHEMBL7731847 | 0.76 | L3MBTL1 (0.41) | PLCG1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |