Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729932 | 0.90 | PLCG1 (0.37) | PLCG1ELANENPC1KMT2APOLB | |
| SCHEMBL7636171 | 0.87 | PLCG1 (0.33) | PLCG1ELANEPOLBSMN1; SMN2 | |
| SCHEMBL7731938 | 0.86 | L3MBTL1 (0.36) | PLCG1ELANERAB9APAX8 | |
| SCHEMBL7722253 | 0.85 | PLCG1 (0.36) | PLCG1ELANENPC1KMT2APOLB | |
| SCHEMBL7730136 | 0.84 | PLCG1 (0.40) | PLCG1ELANE | |
| SCHEMBL6897271 | 0.84 | KDM4E (0.36) | — | |
| SCHEMBL7722380 | 0.79 | PLCG1 (0.34) | PLCG1ELANENPC1KMT2APOLB | |
| SCHEMBL7722339 | 0.79 | PLCG1 (0.34) | PLCG1ELANENPC1KMT2A | |
| SCHEMBL7628844 | 0.77 | PLCG1 (0.34) | PLCG1ELANENPC1KMT2A | |
| SCHEMBL7729305 | 0.77 | PLCG1 (0.35) | PLCG1ELANENPC1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458780-B1 | IMIDAZO(5,1-B)THIAZOLE GROUP AT THE 2-POSITION ON THE CARBAPENEM RING HAVE HIGH ANTI-MICROBIAL ACTIVITIES AGAINST .BETA.-LACTAMASE PRODUCING BACTERIA, MRSA, RESISTANT-PSEUDOMONAS AERUGINOSA, PRSP, ENTEROCOCCI, AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-01 | — | — | US | disclosed |