Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | XBP1 | P17861 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723171 | 0.92 | MAPT (0.56) | TSHRMAPTCTSKCTSSC3AR1 | |
| SCHEMBL7735821 | 0.91 | MAPT (0.47) | TSHRMAPTCTSKCTSSC3AR1 | |
| SCHEMBL7723269 | 0.89 | MAPT (0.48) | TSHRMAPTCTSKCTSSC3AR1 | |
| SCHEMBL7733597 | 0.85 | MAPT (0.51) | TSHRMAPTCTSKCTSSC3AR1 | |
| SCHEMBL5014182 | 0.81 | ALDH1A1 (0.56) | TSHRMAPTCTSKCTSSC3AR1 | |
| SCHEMBL7861048 | 0.80 | C3AR1 (0.44) | TSHRMAPTCTSKCTSSC3AR1 | |
| SCHEMBL5014051 | 0.79 | ALDH1A1 (0.58) | TSHRMAPTCTSKCTSSC3AR1 | |
| SCHEMBL22648524 | 0.78 | C3AR1 (0.47) | TSHRMAPTCTSKCTSSC3AR1 | |
| SCHEMBL801072 | 0.78 | PPARA (0.51) | TSHRMAPTCTSSC3AR1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7735541 | 0.78 | CCR3 (0.41) | MAPTALDH1A1CCR3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |