Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7731056 | 0.93 | PRSS1 (0.38) | DAGLAMMP2LNPEPPRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7733824 | 0.89 | MMP2 (0.39) | DAGLAMMP2OPRK1LNPEPERAP2 | |
| SCHEMBL7733828 | 0.88 | DAGLA (0.38) | DAGLAMMP2LNPEPERAP2ERAP1 | |
| Trifluoroacetic Acid SCHEMBL7732364 | 0.86 | PRSS1 (0.40) | CCR3MMP2LNPEPPRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7732324 | 0.81 | SLC7A11 (0.37) | MMP2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL7732329 | 0.79 | ZAP70 (0.34) | CCR3DAGLAPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL8360682 | 0.79 | LNPEP (0.35) | LNPEPERAP2ERAP1SRCZAP70 | |
| Trifluoroacetic Acid SCHEMBL7723297 | 0.79 | RAB9A (0.41) | SMN1; SMN2HDAC6ALDH1A1MAPTRAB9A | |
| SCHEMBL7730376 | 0.78 | TSHR (0.49) | CCR3SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL7861009 | 0.77 | MMP2 (0.40) | MMP2LNPEPPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |