Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.38 |
| ▸ | RXRB | P28702 | 10/20 | 0.38 |
| ▸ | RARB | P10826 | 7/20 | 0.36 |
| ▸ | RARG | P13631 | 7/20 | 0.36 |
| ▸ | RXRG | P48443 | 6/20 | 0.36 |
| ▸ | RARA | P10276 | 5/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140723 | 0.80 | RXRA (0.44) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL29945228 | 0.80 | RXRA (0.44) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL6086642 | 0.80 | RXRA (0.39) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL6087329 | 0.76 | RXRA (0.39) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL6086569 | 0.75 | RXRA (0.39) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL6087176 | 0.74 | MAP3K14 (0.39) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL6086326 | 0.72 | RXRA (0.39) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL19343350 | 0.72 | GABRA1 (0.43) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL6086519 | 0.71 | MAP3K14 (0.39) | RXRARXRBRARBRARGRXRG | |
| SCHEMBL6234031 | 0.71 | RXRA (0.37) | RXRARXRBRARBRARGRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403638-B1 | COMPOUND FOR USE IN TREATING SKIN DISEASES AND DISORDERS, AND FOR TREATING HYPERVITAMINOSIS A SYNDROME | ALLERGAN SALES, INC. | 2002-06-11 | — | — | US | disclosed |
| WO-2001070662-A2 | 2,4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS | ALLERGAN , INC. (US) | 2001-09-27 | — | — | WO | disclosed |