Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730693 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1HTTTGM2KMT2A | |
| SCHEMBL7730702 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1HTTTGM2KMT2A | |
| SCHEMBL7734016 | 0.92 | TGM2 (0.41) | SMN1; SMN2NPSR1HTTTGM2KMT2A | |
| SCHEMBL7734012 | 0.92 | TGM2 (0.41) | SMN1; SMN2NPSR1HTTTGM2KMT2A | |
| SCHEMBL7734015 | 0.92 | TGM2 (0.41) | SMN1; SMN2NPSR1HTTTGM2KMT2A | |
| SCHEMBL7728748 | 0.91 | LMNA (0.44) | SMN1; SMN2NPSR1HTTTGM2KMT2A | |
| SCHEMBL7728746 | 0.91 | LMNA (0.44) | SMN1; SMN2NPSR1HTTTGM2KMT2A | |
| SCHEMBL7728741 | 0.91 | LMNA (0.44) | SMN1; SMN2NPSR1HTTTGM2KMT2A | |
| SCHEMBL7722007 | 0.88 | TGM2 (0.42) | TGM2KMT2AMEN1MAPTLMNA | |
| SCHEMBL7722003 | 0.88 | TGM2 (0.42) | TGM2KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |