SCHEMBL7731065

SCHEMBL7731065

CCc1cc(F)c(C(F)(F)Oc2cc(F)c(C(F)(F)F)c(F)c2)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.34
PDE2A O00408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733408 0.90 PPARG (0.32) PDE2A
SCHEMBL7731620 0.90 MAOB (0.32) PDE2A
SCHEMBL14749510 0.89 TAAR1 (0.32)
SCHEMBL7723224 0.87 DAO (0.38) DAO
SCHEMBL7732093 0.86 PRMT6 (0.36)
SCHEMBL16922713 0.86 DAO (0.36) DAO
SCHEMBL7730988 0.86 PDE2A (0.33) PDE2A
SCHEMBL7730765 0.85 DAO (0.38) DAO
SCHEMBL7730038 0.84 DAO (0.37) DAO
SCHEMBL12749504 0.84 DAO (0.42) DAOPDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed