Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730668 | 0.92 | MAOB (0.33) | PDE2ATSHR | |
| SCHEMBL7730683 | 0.92 | TSHR (0.35) | PPARGPPARDPPARAPDE2ATSHR | |
| SCHEMBL7731065 | 0.90 | DAO (0.34) | PDE2A | |
| SCHEMBL7730397 | 0.90 | DAO (0.33) | PPARGPPARDPPARA | |
| SCHEMBL7729284 | 0.89 | KIF11 (0.32) | PDE2ATSHR | |
| SCHEMBL7732166 | 0.88 | PPARD (0.35) | PPARDPPARAPDE2ATSHR | |
| SCHEMBL7730994 | 0.87 | FFAR1 (0.33) | TSHR | |
| SCHEMBL7732755 | 0.87 | DAO (0.32) | PPARGPPARAPDE2A | |
| SCHEMBL7731547 | 0.86 | DHODH (0.31) | — | |
| SCHEMBL7730819 | 0.86 | THRB (0.33) | PPARGPPARDPPARAPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |